Research Ideas  

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Welcome to IBD Partners Research Ideas Page!

In this area you will be able to:

  • Propose, vote on, and discuss research ideas
  • View current studies
  • View published research

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You are an active participant in  IBD Partners research prioritization process! Have you ever had a question about IBD that you wish science could answer? Tell us what research is important to you!

Here, you can submit a research idea to the community, cast your votes, and discuss research ideas proposed by other members. Please make your research question as specific as possible. Other members will vote on your research idea, and we will prioritize research ideas with the most votes.

You are allowed to vote for your own proposed research idea if you want. However, you can only vote for a total of five research ideas. If you have already cast your five votes and an idea you like even more is proposed, you can change your votes at any time to reflect your current preferences.

The research team will review all submitted ideas and provide a response to you and to the community. If your idea leads to an IBD Partners Study, you will have the opportunity to serve as a patient collaborator on the research team for that study.

We encourage you to prioritize the ideas that are most important to you, even if the research team determines that your idea is not a good fit for IBD Partners. We will share ideas labeled “Not a Good Fit” with researchers outside of our network when appropriate. We want to make sure all of your votes count!

Thanks for your participation in this important platform to help the IBD research community understand what research questions are important to patients. We are passionate about finding answers to your questions!

How does menopause effect ibd? Can UC change into CD due to hormone changes

I know two other women as well as myself who all agree that had their UC which changed into much worse fully involved crohns after menopause. GIRD, illeum strictures, rectal fishers, stomach and esophagus ulceration, mouth sores...

Women's Health
last activity 10 months ago
10    5
Proposed Idea              

Female menstrual cycle and the worsening of symptoms with each cycle. Is this hormone related and would contraception ease symptoms?

My monthly cycle can often catapult me back into a full on flare and at the least i see a deterioration in my symptoms at this time of my cycle

Women's Health
last activity 10 months ago
30    3

What is the relationship between IBD and hormones? How do the two impact each other?

I have been alternating visits with my GI doc and gynecologist for over a year. We are still having trouble pin pointing if IBD, IBS, or hormones are causing my symptoms. My feeling is that it is all three, and they are causually linked.

Women's Health
last activity 10 months ago
15    4

What is the effect of hormones, particularly increased estrogen, on Crohn's disease.

The common statement is that 1/3 of Crohn's patients feel better or go into remission during pregnancy. Why? Is there a way to be able to replicate the "pregnancy effect" when patients are not pregnant.

Women's Health
last activity 10 months ago
61    8
Proposed Idea              

Is there a relationship between maternal, fetal, or early childhood infection and the development of IBD later in life?

My mother contracted shingles when she was pregnant with me. I believe my Crohn's could potentially be related to prenatal immune stress caused by my mother's infection. Mothers and fetuses share hormones, immune cells and other factors that could impact the development of the immune system in the fetus. A potential mechanism for this could involve epigenetic changes in the expression of genes related to immunity.

Women's Health
last activity almost 2 years ago
9    0
Proposed Idea              

Do hormones affect IBD flares?

Many women seem to experience more GI symptoms during their period. Perhaps the onset of IBD is linked to a hormonal imbalance which manifests by attacking the gut.

Women's Health
last activity almost 2 years ago
7    0
Proposed Idea              

Is IBD/flaring commonly associated with gynecologic manifestations, such as lichen sclerosus or localized inflammation at the labia/vaginal vault?

There's a lot of information available about some specific extra-intestinal manifestations, but not in this area. More than 50% of the IBD Partners participants are female, and studies already document a correlation between hormones and flaring.

Women's Health
last activity about 1 year ago
0    0

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