Research Ideas  

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Welcome to IBD Partners Research Ideas Page!

In this area you will be able to:

  • Propose, vote on, and discuss research ideas
  • View current studies
  • View published research

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You are an active participant in  IBD Partners research prioritization process! Have you ever had a question about IBD that you wish science could answer? Tell us what research is important to you!

Here, you can submit a research idea to the community, cast your votes, and discuss research ideas proposed by other members. Please make your research question as specific as possible. Other members will vote on your research idea, and we will prioritize research ideas with the most votes.

You are allowed to vote for your own proposed research idea if you want. However, you can only vote for a total of five research ideas. If you have already cast your five votes and an idea you like even more is proposed, you can change your votes at any time to reflect your current preferences.

The research team will review all submitted ideas and provide a response to you and to the community. If your idea leads to an IBD Partners Study, you will have the opportunity to serve as a patient collaborator on the research team for that study.

We encourage you to prioritize the ideas that are most important to you, even if the research team determines that your idea is not a good fit for IBD Partners. We will share ideas labeled “Not a Good Fit” with researchers outside of our network when appropriate. We want to make sure all of your votes count!

Thanks for your participation in this important platform to help the IBD research community understand what research questions are important to patients. We are passionate about finding answers to your questions!

Proposed Idea              

Examine the relation of Vitamin D deficiency possible contributing cause to IBD, beyond simple correlative data. Specifically Vit D involvement in immune development.

There is a well known increase in IBD in more western nations as well as higher latitudes. With most Western societies spending large amounts of time indoors at home, in cars, and at their employment, it's easy to see a causitive relation to decreased vitamin D in these populations. The increased latitude of Canada and Nordic countries also contributes low vitamin D levels in general population. Both of these population groups (Western Urban, and High latitudes) have increased incidence of IBD. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3166406/ Provides a simple primer on Vit D relation to immune system development and maintenance; as well is it's deficiency in a host of autoimmune disorders. I would like to see a multi arm study along the following investigation paths: 1) Vit D testing for newly diagnosed. Followed by surveillance testing throughout treatment w/ and w/o vit supplementation arms. 2) Genetic testing for IBD markers/alleles in relation to Vit D levels (i.e. is the deficiency related to turning "on" various epigenetic and genetic markers that are present in active IBD). 3) Genetic testing of IBD markers, Vit D testing, and Gut microflora testing of non-active/IBD free family members for comparison of gene expression and interdependence between these factors, possibly prospective following of same patients if diagnosed offspring.

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last activity about 1 year ago
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