Research Ideas  

×
Welcome to IBD Partners Research Ideas Page!

In this area you will be able to:

  • Propose, vote on, and discuss research ideas
  • View current studies
  • View published research

Show More

You are an active participant in  IBD Partners research prioritization process! Have you ever had a question about IBD that you wish science could answer? Tell us what research is important to you!

Here, you can submit a research idea to the community, cast your votes, and discuss research ideas proposed by other members. Please make your research question as specific as possible. Other members will vote on your research idea, and we will prioritize research ideas with the most votes.

You are allowed to vote for your own proposed research idea if you want. However, you can only vote for a total of five research ideas. If you have already cast your five votes and an idea you like even more is proposed, you can change your votes at any time to reflect your current preferences.

The research team will review all submitted ideas and provide a response to you and to the community. If your idea leads to an IBD Partners Study, you will have the opportunity to serve as a patient collaborator on the research team for that study.

We encourage you to prioritize the ideas that are most important to you, even if the research team determines that your idea is not a good fit for IBD Partners. We will share ideas labeled “Not a Good Fit” with researchers outside of our network when appropriate. We want to make sure all of your votes count!

Thanks for your participation in this important platform to help the IBD research community understand what research questions are important to patients. We are passionate about finding answers to your questions!

What is the comparative safety and efficacy of natural supplements (vitamin D, fish oil, turmeric) commonly used in IBD versus prescription medications?

Many of us try natural supplements instead of or in addition to prescription medications in the management of IBD. Are natural supplement products more safe or effective when compared to prescription medications? Is combining natural supplements with prescription treatments more effective?

Alternative Therapies
last activity 15 days ago
30    4

Comorbidities of Neurological conditions and IBD

Recent data (Kigerl et al. 2016 (JEM), Bourassa et al. (Neuroscience Letters) and others) have suggested that dysbiosis in the gut, similar to that observed in IBD can affect both recovery following neurological injury and general neurological health. Examining reported levels of comorbidity could provide insights into whether further study of these relationships is warranted. This would, hopefully, lead to better outcomes for both neurology and IBD patients.

Other
last activity 9 months ago
5    3

Compare symptoms of IBD patients who consume dairy and those who avoid dairy.

“Milk fats increase the amount of taurine conjugated bile acids that promote growth and metabolic activ ity of sulphate reducing, bile acid tolerant bacterial species, which in turn stimulate pathogenic immune responses in genetically susceptible hosts” Sartor, R. B. Nat. Rev. Gastroenterol. Hepatol. 9, (2012)

Diet
last activity 4 months ago
82    4

What percentage of patients who have colons removed or resectioned have been "cured" of their IBD?

Gives insight into options other than medication when nothing else has worked.

Procedures And Testing
last activity 9 months ago
9    3

Association between oral hygiene and gut inflammation

Mouth problems have been associated with IBD, however, these problems have historically been explained as a symptom of IBD. I would like the hypothesis tested that mouth problems (e.g. possibly due to an altered oral microbiome) may be a trigger of inflammation, and not a symptom (i.e. good oral hygiene is associated with less gut inflammation). Background information: It has been shown that the oral microbiome in IBD patients differs compared to healthy controls (https://www.ncbi.nlm.nih.gov/pubmed/21987382). Anecdotal evidence: I notice a worsening of symptoms when I do not regularly floss. I'm an epidemiologist, so I know there is little value in anecdotal evidence, but still wanted to share my thinking!

Lifestyle
last activity 9 months ago
7    1

Is the gut flora of people with IBD similar to people with depression and/or anxiety? I propose exploring a connection between the microbiota associated with IBD and mental health disorders.

I believe this question to be important because disruption of the gut flora is implicated in autoimmune diseases, obesity and mental illness and finding connections could broaden the medical community's approach in treating all of the above. I also think the designation of these illnesses as primarily "western illnesses" is interesting, particularly given how our food system functions (antibiotic use in meat production, use of bleach on salad greens, etc).

Microbiome
last activity 8 months ago
30    1

We need to develop a better understanding of how nutrition as a whole affects IBD and put together a more comprehensive diet plan that includes the definite triggers.

Food has always been a contributing factor in my flares of Crohn's Disease, but the original recommendation by my doctors 20 years ago has turned out to be not only false, but the complete opposite of what I needed to be eating for my illness. I have recently started working on figuring out a better plan for my eating habits and have discovered a few things that I would like validated by research.

Diet
last activity 2 months ago
47    2

What are some modifiable lifestyle habits that have the most significant effects on IBD disease activity?

It would be great if we could identify key modifiable habits that effect disease activity (positive and negative) in order to understand ways to minimize disease activity? Some measures I would propose studying include: amount of sleep, alcohol use, smoking, hours worked per day or days per year, exercise, weight management, frequency of social/family interaction.

Lifestyle
last activity 6 months ago
9    2

Can positive emotions favorably influence IBD patient status?

Research tends to focus on negative emotional state (depression) and the potential downside. Work by Dr B. Fredrickson shows positive emotions can provide favorable health impact and has developed a simple on line tool to measure positive emotions which could be incorporated into this site to do research going forward.

Other
last activity over 2 years ago
8    1

Propose Research Idea


Published Studies VIEW ALL
Trends and Characteristics of Clinical Trials Participation for Inflammatory Bowel Disease in the United States: A Report From IBD Partners

Read Study
Diet Low in Red and Processed Meat Does Not Reduce Rate of Crohn’s Disease Flares

Read Study
Impact of Obesity on Disease Activity andPatient-Reported Outcomes Measurement InformationSystem (PROMIS) in Inflammatory Bowel Diseases

Read Study

Active Studies VIEW ALL
The Effects of Antidepressant Medication and Social Support on Disease Progression in IBD Patients

Read Study
Psychological Factors Associated with Adherence to Oral Treatment in IBD

Read Study
Rare IBD Characteristics Study

Read Study

Want to Join the Network?

Do you have Crohn's disease or ulcerative colitis? Join other patients and the IBD research community to help us all learn more about IBD together.

Join

Already a Member? Sign in.
Are you a researcher? Click here.
Under age 18? Join IBD Partners Kids & Teens.